Are stem cell niches shared for skin cancers?
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چکیده
منابع مشابه
Stem Cell Niches for Skin Regeneration
Stem cell-based therapies offer tremendous potential for skin regeneration following injury and disease. Functional stem cell units have been described throughout all layers of human skin and the collective physical and chemical microenvironmental cues that enable this regenerative potential are known as the stem cell niche. Stem cells in the hair follicle bulge, interfollicular epidermis, derm...
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Stem cells are required to support the indeterminate growth style of plants. Meristems are a plants stem cell niches that foster stem cell survival and the production of descendants destined for differentiation. In shoot meristems, stem cell fate is decided at the populational level. The size of the stem cell domain at the meristem tip depends on signals that are exchanged with cells of the org...
متن کاملArtificial stem cell niches.
Stem cells are characterized by their dual ability to reproduce themselves (self-renew) and specialize (differentiate), yielding a plethora of daughter cells that maintain and regenerate tissues. In contrast to their embryonic counterparts, adult stem cells retain their unique functions only if they are in intimate contact with an instructive microenvironment, termed stem cell niche. In these n...
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1. The anatomically simplest GSC niche in C. elegans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. The first structurally and functionally defined GSC niche in the Drosophila ovary . . . . . . . . . . . . . . . . . . . . 4 3. The structurally and mechanistically well-studied GSC niche in the Drosophila testis . . . . . . . . . . . . . . . . . 6 4...
متن کاملBiomolecular Blocks for Artificial Stem Cell Niches
Introduction The expansion of adult stem cells in their undifferentiated phenotype is a crucial step for their use in regenerative medicine. However, the cell culture substrates currently available cannot ensure the control of the cell multi-potent characteristics. It has been suggested that artificial substrates mimicking the histological features of stem cell niches may provide an appropriate...
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ژورنال
عنوان ژورنال: Pigment Cell & Melanoma Research
سال: 2010
ISSN: 1755-1471
DOI: 10.1111/j.1755-148x.2010.00727.x